New research provides evidence for a link between vitamin D insufficiency and asthma severity. Serum vitamin D levels in more than 600 children were inversely linked to several indicators of allergy and asthma severity.
While previous studies have suggested that vitamin D may affect how airway cells respond to treatment with inhaled steroids, this is the first study of vitamin D and disease severity in children with asthma.
Children with lower vitamin D levels were significantly more likely to have been hospitalized for asthma in the previous year, tended to have airways with increased hyperreactivity, and were likely to have used more inhaled corticosteroids -- all signifying higher asthma severity. These children were also significantly more likely to have several markers of allergy, including dust-mite sensitivity.
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